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Alzheimer's Disease

Alzheimer’s disease is a condition of dementia it both progressive and degenerative brain disease Alzheimer is the severe form of dementia named after the great neurologist Dr. Alois Alzheimer it mainly affects the part of brain with memory function. behavior and thinking and memory is affected by the progression of dementia usually the elder people are at risk of this condition. It is a kind of progressive neurodegenerative disorder associated with the abnormality in cognitive functions such as thinking, memory, reasoning and behavioral skills. The Alzheimer disease initially affects its victims with the preliminary symptoms being lack of orientation and memory loss, but in further stages the disease can progress to a level of complete dependency on others for the basic activities of daily living. Doctors says that a there are many of causes other then genetics and age, are responsible for the onset and development of this disorder.

Like all other forms of dementia the Alzheimer is also caused by severe nerve damage, mainly due to the formation of proteinaceous plaques. There are two main reason of Alzheimer's mainly deposition of tangles inside the brain cells and amyloid proteins blocking the pathways between the neurons, these formation affects smooth passage of impulse from motor neurons to target organs ultimately resulting in their death or degeneration. The main cause of these formations is not identified yet , but scientists are relating some genetic changes to be associated with them.

Symptom

  • Memory loss
  • Difficulty in performing task
  • Lack of orientation to time and places
  • Poor and wrong judgment
  • Misplacing things
  • Changes in behavior
  • Changes in personality

Stem cell therapy for treatment of Alzheimer

Conventionally only supportive treatments are present to temporarily relieve the pain and symptoms, additionally there are many services management of some activities and programs such counseling and nursing homes. Although the damage in case of death of neurons cannot be stopped or reversed with this treatment .

Stem cells are cell of the body which differentiating into the required type of cells upon given a proper growth factors and stimulants in vitro. The stem cell therapy focuses on giving the sufficient number of Adult Stem Cells which will travel into multiple parts of the brain where the damage has occurred. Transplanted stem cells are having potential to transform into new neurons cells which are needed for the replacement of damaged neurons. They also help in creating a background that will secrete some of the stimulants required for making connections to replace lost parts of the nervous system.

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